COVID-19: NCDC adopt new treatment regimen          

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The Nigeria Centre for Disease Control, NCDC, has tweaked its recommendation for the treatment of coronavirus patients in order to conform to new realities.

The development was part of the updates the Presidential Taskforce on COVID-19 provided at Thursday’s press briefing of the committee.

NCDC Director General, Dr Chikwe Ihekweazu, said the agency has made some changes in the treatment regimen for the novel virus saying: “We have also removed the use of antivirals from our treatment guidelines. Like the minister just said, the trials for chloroquine and hydroxychloroquine will still go on.”

Ihekwazu explained that some of the regimen changes were informed partly by new data from Singapore that showed that RNA detected beyond 10 days is no longer infectious as no viable virus is grown by a viral culture.

According to him, “There have been new science emerging about the duration of infectivity of individual patients. It led to the WHO issuing new clinical guidelines.

“We then convened colleagues across our organisation, the department of hospital services of the Federal Ministry of Health, as well as other colleagues with whom we work, to review our guidelines and issue new guidelines for the country, and of course adapting it to local circumstances.

“The key thing is that the management of COVID-19 will be made primarily supportive; we don’t have any treatment so far that has any proven impact on morbidity.

“One of the major changes that have happened is the discharge criteria. While these guidelines are obviously and primarily targeted at physicians managing patients, it is important that patients and people know. There are two groups of patients –  symptomatic and asymptomatic patients.

“For symptomatic patients, they may now be discharged at least 10 days after symptoms onset and at least three days without symptoms. If your symptoms last for longer, we will wait for longer managing you supportively.

“If you are asymptomatic, you can be discharged 14 days after your first positive test. So, we no longer have to wait for a negative test to discharge. This way you can go home with confidence that you are no longer infective and you’re not putting your family and friends or anyone else at risk.

“We are not encouraging that people be discharged while they are still symptomatic. We are talking about discharging people that are asymptomatic and have recovered. That is, you are symptomatic and have recovered or you are completely asymptomatic throughout your clinical episodes.

“At that point, you really don’t need more clinical interventions, even at home; you just need time to recover. It is just like you recover from any other illness. You don’t need any special intervention once you have been discharged.

“Change is difficult because we have been saying you have to have the negative test. Even though we have published these results, many physicians are still not using them. We can assure them and everyone managing cases that 14 days after, in fact, 10 days is what the evidence says.

“But we have added 14 days to make it two weeks for people to then discharge for patients that are asymptomatic.”

 

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